RJMPDRN®REC e emela tsoelo-pele e kholo ea metsoako ea litlolo e thehiloeng ho nucleic acid, e fanang ka PDRN e kopantsoeng ea saalmon e entsoeng ka biotechnology. Traditional PDRN e ntšitsoe haholo-holo ho tsoa ho salmon, ts'ebetso e qobelloang ke litšenyehelo tse phahameng, phapang ea batch-to-batch, le bohloeki bo fokolang. Ho feta moo, ho itšetleha ka lisebelisoa tsa tlhaho ho baka mathata a ts'ireletseho ea tikoloho le ho fokotsa sekhahla ho fihlela tlhoko e ntseng e hola ea mmaraka.
RJMPDRN®REC e sebetsana le liqholotso tsena ka ho sebelisa mefuta ea libaktheria tse entsoeng ka boenjiniere ho etsa likhechana tsa PDRN, e nolofalletsang motsoako o laoloang ha e ntse e boloka boleng ba ho ikatisa le ho fokotsa tšusumetso ea tikoloho.
Mokhoa ona oa ho kopanya hape o lumella moralo o nepahetseng oa tatellano e sebetsang, e hlahisang lihlahisoa tsa nucleic acid tse etselitsoeng litlamorao tse ikhethang tsa bioactive. Boima ba limolek'hule le sebopeho sa sebopeho sa likhechana li laoloa ka thata, ho matlafatsa ho tšoana le ho kenella ha letlalo. E le motsoako o se nang liphoofolo, RJMPDRN®REC e hokahana le litekanyetso tsa taolo ea lefats'e, e holisa kamohelo ea 'maraka libakeng tse hlokolosi. Ts'ebetso ea tlhahiso e latela litekanyetso tse thata tsa boleng, ho sebelisoa mekhoa ea ho belisoa le ho hloekisa e fanang ka boleng bo tsitsitseng, bohloeki bo phahameng, le phepelo e tšepahalang-ho sebetsana le litšenyehelo, ketane ea phepelo le liphephetso tsa tikoloho tsa ho ntšoa ho tloaelehileng.
Physicochemically, RJMPDRN®REC ke phofo e tšoeu, e qhibilihang ka metsing e entsoeng ka DNA e nang le RNA e nyenyane, e nkiloeng ho salmon PDRN tatellano, 'me e bonts'a pH ea 5.0-9.0. E khethiloe e le motsoako oa boemo ba litlolo o loketseng ho sebelisoa li-emulsion tsa boemo bo holimo, litlolo, li-patches tsa mahlo, limaske le litlolo tse ling tsa premium skincare. Lithuto tsa in vitro li bontšitse polokeho le katleho ea eona maemong a 100-200 μg / mL, e tšehetsang ho ata ha lisele le ts'ebetso e khahlanong le ho ruruha ntle le cytotoxicity.
Lithuto tsa katleho li boetse li totobatsa bioactivity e phahameng ea RJMPDRN®REC. E matlafatsa haholo ho falla ha fibroblast, ho finyella sekhahla sa ho ata ha 131% ka lihora tse 41 ha ho bapisoa le ho laola. Mabapi le motsoako oa collagen, RJMPDRN®REC e khothalletsa batho ba mofuta oa I collagen ka makhetlo a 1.5 le mofuta oa III oa collagen ka makhetlo a 1.1 a amanang le taolo, ho feta PDRN e tloaelehileng e nkiloeng ke saalmon. Ho feta moo, e thibela haholo bakena-lipakeng ba ho ruruha joalo ka TNF-α le IL-6. Ha e kopantsoe le sodium hyaluronate, , RJMPDRN®REC e bonts'a litlamorao tsa synergistic, e eketsang phallo ea lisele, e bonts'a bokhoni bo matla ba ho hlophisoa ha tšebelisano molemong oa ho nchafatsa le ho thibela botsofali.
Ka kakaretso, RJMPDRN®REC e kenyelletsa ho tlola ho hoholo ha thekenoloji ho tloha ts'ebetsong ea setso ho ea ho biotechnological synthesis, e fana ka mefuta e meng e ka hlahisoang hape, e hloekileng haholo, le e tšoarellang bakeng sa litlolo tsa maemo a holimo tsa tlhokomelo ea letlalo. E bonts'a bioactivity, profil ea polokeho, le scalability e e beha e le motsoako oa maano bakeng sa lihlahisoa tsa litlolo tse shebaneng le botsofali, tokiso ea letlalo, le bophelo bo botle ba letlalo, tse tsamaellanang ka botlalo le tlhokahalo e tsoelang pele ea metsoako ea litlolo e tšoarellang le e netefalitsoeng ke mahlale.
Tobetsa mona ho ithuta haholoanyane ka sehlahisoa sena.
Nako ea poso: Aug-28-2025